15 gm Itraconazole Gel

15 gm Itraconazole Gel is antifungal formulation which is prescribed for treatment of aspergillosis, blastomycosis, histoplasmosis, and coccidioidomycosis. It is known to work by inhibiting lanosterol 14alpha demethylase which results in inhibition of ergosterol synthesis. Itraconazole has chemical formula C35H38Cl2N8O4 with molar mass of 705.64 g/mol. It gets metabolized in liver with help of CYP3A4 enzyme having protein binding ability of 99.8%. 15 gm Itraconazole Gel belongs to triazole family of medicines and shows elimination half life of about 21 hours and gets excreted in feces & urine. It is highly effective in nature but use in pregnancy must be under proper guidance of doctor.